USGENE provides the complete archive of all USPTO patent sequence data. As of February 5, 2015 there are 191 million sequence records in USGENE, captured from 232,000 patents and published applications. The latest statistics are available here.
Yes, USGENE is available via the SequenceBase Research Portal using a fixed fee annual subscription pricing model. Limited short term free trials of USGENE are available upon request via the feedback form.